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Comprar Afilta (Brand name: Apcalis SX) Online

  • €1.46
  • Brand name: Apcalis SX
  • Disponibilidad: En stock
  • Ingrediente activo: Tadalafil
Afilta es una solución de gelatina utilizado para el tratamiento de la disfunción eréctil masculina llamada impotencia.
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20 mg
Nombre del producto Por píldora Por paquete  
10 píldoras €3.17 €31.65
20 píldoras €2.20 €63.30 €44.07
30 píldoras €1.88 €94.95 €56.50
60 píldoras €1.56 €189.90 €93.76
90 píldoras €1.46 €284.85 €131.03

INDICATIONS

Afilta is a jelly solution for the treatment of male erectile dysfunction. Afilta increases blood flow to the penis allowing more blood flow into the penis like happened naturally when a man is sexually stimulated. With more blood flowing in and less flowing out, the arteries in the penis enlarge resulting erection.

INSTRUCTIONS

For most patients, Afilta should be taken once a day as needed. In patients taking certain protease inhibitors (such as for the treatment of HIV), it is recommended to not exceed a maximum single dose of 25 mg of Afilta in a 48-hour period.

If you miss a dose of this medicine, take it as soon as possible. Do not take 2 doses at once.

DOSAGE 

In most cases the dosage should not increase more than once in a day (24 hours).
For people who consume protease inhibitors (used in treatment of HIV), the dosage should not be more than a single dose of 25 mg of Afilta within 48 hours.

If you miss out on a dose, then take it as soon as you remember about it. But keep in mind that you will have to adjust your next dose by spacing it out by 4 to 5 hours. If this is not possible, then the best thing to do would be to skip the missed dose and continue with your normal dosage schedule.

Never try to compensate for the missed dose by taking a double dose together. It may cause adverse effects.

STORAGE

Afilta should be stored at room temperature, 15-30 degrees C (59-86 degrees F). Keep Afilta out of the reach of children.

MORE INFO: 

Drinking alcohol can temporarily impair the ability to get an erection. To get the maximum benefit from your medication, you are advised not to drink large amounts of alcohol before taking Afilta.

 

SAFETY INFORMATION

Before you start any treatment with Afilta, be sure to ask your healthcare provider if your heart is healthy enough.

If you're a man who uses nitrate drugs, like nitroglycerine, never take Afilta. The combination of Afilta and nitrates can make your blood pressure suddenly drop to unsafe levels. You could get dizzy, faint, or even have a heart attack or stroke. Nitrates are found in many prescription medications that are used to treat angina (chest pain due to heart disease).

If you are not sure, whether any of your medications contain nitrates, or if you do not understand what nitrates are, ask your healthcare provider or pharmacist.

Discuss your past/current medical history in detail with your doctor before beginning treatment with any new medication. Ask your doctor if your heart is healthy enough before starting with this medication.
Doctors advise against using Afilta if you are allergic to any ingredient in it or if you use nitrate drugs, like nitroglycerine. The combined effect of Afilta and nitrates can make your blood pressure suddenly drop. It can also make you dizzy, faint, or even have a heart attack or stroke.

SIDE EFFECTS

If you experience any of the following serious side effects, stop taking Afilta and seek emergency medical attention or notify your doctor immediately:

  • sudden vision loss; 
  • ringing in your ears, or sudden hearing loss; 
  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
  • irregular heartbeat; 
  • swelling in your hands, ankles, or feet; 
  • shortness of breath;
  • vision changes;
  • feeling light-headed, fainting; or
  • penis erection that is painful or lasts 4 hours or longer. 


Less serious side effects may include:

  • warmth or redness in your face, neck, or chest;
  • stuffy nose;
  • headache;
  • upset stomach; or
  • back pain. 


This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

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Para evitar pasar a través de cualquier situación adversa y evitar efecto secundario alguno, tendría que considerar las precauciones, advertencias, así como las contraindicaciones con el propósito de no pasar por incidencia adversa alguna o por algún que otro efecto secundario, pero a veces ocurre que un paciente hipersensible sufre reacciones negativas de diferente envergadura que luego enumeraremos. Llame a su médico en línea o a su médico personal tan pronto como observan estos efectos para evitar consecuencia grave alguna:

Rare

  • Painful or prolonged erection of the penis
  • Changes in color vision

More Common

  • Acid or sour stomach
  • belching
  • heartburn
  • indigestion
  • stomach discomfort, upset, or pain

Less Common

  • Arm, back, or jaw pain
  • blurred vision
  • chest pain or discomfort
  • chest tightness or heaviness
  • chills
  • cold sweats
  • confusion
  • dizziness
  • fainting
  • faintness or lightheadedness when getting up suddenly from a lying or sitting position
  • fast or irregular heartbeat
  • headache
  • hearing loss
  • nausea
  • nervousness
  • pain or discomfort in the arms, jaw, back, or neck
  • pounding in the ears
  • shortness of breath
  • slow or fast heartbeat
  • sweating
  • unusual tiredness or weakness
  • vomiting
  • Bloody nose
  • body aches or pain
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • burning, dry, or itching eyes
  • burning feeling in the chest or stomach
  • congestion
  • difficulty with moving
  • difficulty with swallowing
  • dry mouth
  • dryness or soreness of the throat
  • excessive eye discharge
  • eye pain
  • feeling of constant movement of self or surroundings
  • feeling of warmth, redness of the face, neck, arms and occasionally, upper chest
  • fever
  • hoarseness
  • increased erection
  • lack or loss of strength
  • loose stools
  • muscle aching or cramping
  • muscle stiffness
  • nasal congestion
  • neck pain
  • pain
  • pain in the arms or legs
  • pain or burning in the throat
  • redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
  • reduced sensitivity to touch
  • runny nose
  • sensation of spinning
  • sleepiness or unusual drowsiness
  • sleeplessness
  • spontaneous penile erection
  • stomach upset
  • swelling of the eyelids
  • swelling or puffiness of the eyes or face
  • swollen joints
  • tearing
  • tender, swollen glands in the neck
  • tenderness in the stomach area
  • trouble with sleeping
  • unable to sleep
  • upper abdominal or stomach pain
  • voice changes
  • watering of the eyes

Incidence Not Known

  • Abdominal or stomach pain
  • blindness
  • blistering, peeling, or loosening of the skin
  • cough
  • cracks in the skin
  • decrease or change in vision
  • diarrhea
  • difficulty with speaking
  • double vision
  • fast, irregular, pounding, or racing heartbeat or pulse
  • headache, severe and throbbing
  • hives or welts
  • inability to move the arms, legs, or facial muscles
  • inability to speak
  • itching
  • joint or muscle pain
  • loss of heat from the body
  • numbness or tingling of the face, hands, or feet
  • red irritated eyes
  • red skin lesions, often with a purple center
  • red, swollen skin
  • redness of the skin
  • redness or soreness of the eyes
  • scaly skin
  • skin rash
  • slow speech
  • sores, ulcers, or white spots in the mouth or on the lips
  • sudden cardiac death
  • swelling of the feet or lower legs
Type Small Molecule
Accession Number DB00820  (APRD00071)
Groups Approved, Investigational
Synonyms
  • (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
  • (6R,12AR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
  • 6-BENZO[1,3]dioxol-5-yl-2-methyl-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
  • ICOS 351
  • Tadanafil
UNII 742SXX0ICT
CAS number 171596-29-5
Weight Average: 389.404
Monoisotopic: 389.137556111
Chemical Formula C22H19N3O4
InChI
InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1
IUPAC Name
(2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0³,⁸.0¹¹,¹⁶]heptadeca-1(10),11,13,15-tetraene-4,7-dione
Protein binding

94%

Toxicity

Oral, Rat LD50 = 2000 mg/kg, no deaths or toxicity.

Half life

17.5 hours

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