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Comprar Xeloda Online

  • €13.37
  • Disponibilidad: En stock
  • Ingrediente activo: Capecitabine
Xeloda (Capecitabine) es utilizada para tratar las mujeres con cáncer del seno que es resistente a otros fármacos utilizados más comúnmente.
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500 mg
Nombre del producto Por píldora Por paquete  
10 píldoras €16.72 €167.17
20 píldoras €14.49 €334.34 €289.77
30 píldoras €13.75 €501.52 €412.36
40 píldoras €13.37 €668.69 €534.95

INDICATIONS

Xeloda (capecitabine) is a cancer medication that interferes with the growth of cancer cells and slows their spread in the body.
It is used to treat breast cancer and colon or rectum cancer that has spread to other parts of the body.
Xeloda may also be used for other purposes not listed in this medication guide.

INSTRUCTIONS 

Take Xeloda exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Xeloda is usually given in a treatment cycle of 2 weeks on and 1 week off. This 3-week cycle is repeated up to 8 times (24 weeks). Your Xeloda dosage may be different. Follow your doctor's instructions.

During the weeks when you take Xeloda, take the medication once in the morning and once in the evening, unless your doctor tells you otherwise. You may also be given other medications as part of a combination cancer treatment.

Xeloda should be taken with food or within 30 minutes after eating a meal. Take this medication with a full glass (8 ounces) of water.

To be sure this medication is not causing harmful effects, your blood may need to be tested on a regular basis. Your kidney and liver function may also need to be tested. Do not miss any follow-up visits. You must remain under the care of a doctor while you are taking Xeloda.

DOSAGE 

Use xeloda as directed by your doctor.

If you missed a dose take it as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

STORAGE 

Store Xeloda at room temperature away from moisture and heat. Keep it tightly closed when not in use.

MORE INFO: 

Active Ingredient: capecitabine

SAFETY INFORMATION

Do NOT use Xeloda if:

You should not take Xeloda if you are allergic to capecitabine or fluorouracil (Adrucil), or if you have severe kidney disease or a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency. Do not use Xeloda if you are pregnant. It could harm the unborn baby. Use effective birth control while you are taking Xeloda, whether you are a man or a woman. Tell your doctor if a pregnancy occurs during treatment. You should not breast-feed while you are taking Xeloda.

Before you take Xeloda, tell your doctor if you have liver or kidney disease, a history of coronary artery disease, or if you are also taking folic acid (contained in many vitamin and mineral supplements), leucovorin (Wellcovorin), phenytoin (Dilantin), or a blood thinner (warfarin, Coumadin).

While taking Xeloda, you will need blood tests at your doctor's office on a regular basis. Do not miss any appointments. You must remain under the care of a doctor while you are taking Xeloda.

Call your doctor at once if you have a serious side effect such as severe vomiting or diarrhea, fever or flu symptoms, pain or redness of your hands or feet, jaundice (yellowing of the skin or eyes), chest pain, sudden numbness or weakness, or fainting. 

FDA pregnancy category D. Do not use Xeloda if you are pregnant. It could harm the unborn baby.

Use birth control to prevent pregnancy while you are taking Xeloda, whether you are a man or a woman. Tell your doctor if a pregnancy occurs during treatment.

It is not known whether capecitabine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking Xeloda. People over 80 years old may be more likely to have certain side effects from Xeloda.

Important safety information: 

Tell your doctor about all other medications you use, especially:


bosentan (Tracleer);

fluoxetine (Prozac);

fosphenytoin (Cerebyx);

montelukast (Singulair) or zafirlukast (Accolate);

rifampin (Rifater, Rifadin, Rifamate);

selegiline (Eldepryl, Emsam, Zelapar);

voriconazole (Vfend);

cancer medication such as paclitaxel (Taxol) or tamoxifen (Soltamox);

heart or blood pressure medications such as amiodarone (Cordarone, Pacerone), carvedilol (Coreg), losartan (Hyzaar, Cozaar), or torsemide (Demadex);

type 2 diabetes medications such as glimepiride (Amaryl), glipizide (Glucotrol), nateglinide (Starlix), pioglitazone (Actos, Actoplus Met), repaglinide (Prandin), rosiglitazone (Avandia, Avandamet), or tolbutamide (Orinase); or

sulfa drugs (Bactrim, Gantanol, Gantrisin, Septra, SMX-TMP, and others).

This list is not complete and there may be other drugs that can interact with Xeloda. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

SIDE EFFECTS

Get emergency medical help if you have any of these signs of an allergic reaction to Xeloda: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:


severe diarrhea (more than 4 times per day, or during the night);

vomiting (more than once in 24 hours);

nausea, loss of appetite, eating much less than usual;

weakness, feeling light-headed, hot or dry skin;

pain, tenderness, redness, swelling, blistering, or peeling skin on your hands or feet;

fever, chills, body aches, flu symptoms;

swelling, white patches, or sores in your mouth or throat;

jaundice (yellowing of the skin or eyes);

chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;

sudden numbness, weakness, headache, confusion, or problems with vision, speech, or balance; or

slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).


Less serious Xeloda side effects may include:

stomach pain or upset, constipation;

tired feeling;

temporary hair loss;

mild skin rash;

headache, dizziness;

altered sense of taste;

back pain, joint or muscle pain;

eye irritation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

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Para evitar pasar a través de cualquier situación adversa y evitar efecto secundario alguno, tendría que considerar las precauciones, advertencias, así como las contraindicaciones con el propósito de no pasar por incidencia adversa alguna o por algún que otro efecto secundario, pero a veces ocurre que un paciente hipersensible sufre reacciones negativas de diferente envergadura que luego enumeraremos. Llame a su médico en línea o a su médico personal tan pronto como observan estos efectos para evitar consecuencia grave alguna:

Rare

  • Bone pain
  • change in color of treated skin
  • difficulty with walking
  • discouragement
  • feeling of constant movement of self or surroundings
  • feeling sad or empty
  • full or bloated feeling or pressure in the stomach
  • general feeling of discomfort or illness
  • hot flushes
  • impaired balance
  • increased sweating
  • joint pain
  • lack of appetite
  • loss of interest or pleasure
  • muscle weakness
  • noisy breathing
  • pain in the rectum
  • pain, swelling, or redness in the joints
  • passing less gas
  • rough, scratchy sound to voice
  • runny nose
  • sensation of spinning
  • shakiness in the legs, arms, hands, or feet
  • shivering
  • sores on the skin
  • swelling of abdominal or stomach area
  • tremor or shaking of the hands or feet
  • trouble concentrating
  • voice changes

More Common

  • Abdominal or stomach pain
  • diarrhea
  • loss of fingerprints
  • nausea
  • numbness, pain, tingling, or other unusual sensations in the palms of the hands or bottoms of the feet
  • pain, blistering, peeling, redness, or swelling of the palms of the hands or bottoms of the feet
  • pain, redness, swelling, sores, or ulcers in your mouth or on your lips
  • unusual tiredness or weakness
  • vomiting

Less Common

  • Burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
  • changes or discoloration in the fingernails or toenails
  • difficulty with moving
  • discouragement
  • headache
  • heartburn
  • increased sensitivity of the skin to sunlight
  • muscle pain
  • pain
  • pain and redness of the skin at the place of x-ray treatment
  • pain in the joints or limbs
  • red, sore eyes
  • sunken eyes
  • thirst
  • trouble sleeping
  • weakness
  • wrinkled skin

Incidence Not Known

  • Chest discomfort, tightness, or heaviness
  • dilated neck veins
  • dizziness
  • extreme fatigue
  • irregular breathing
  • no blood pressure or pulse
  • pain or discomfort in the arms, jaw, back, or neck
  • stopping of heart
  • sweating
  • unconsciousness
  • weight gain
Type Small Molecule
Accession Number DB01101  (APRD00203)
Groups Approved, Investigational
Synonyms
  • (1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-carbamic acid pentyl ester
  • Capecitabin
  • Capecitabina
  • Capecitabinum
  • Pentyl [1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate
  • Pentyl 1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate
UNII 6804DJ8Z9U
CAS number 154361-50-9
Weight Average: 359.3501
Monoisotopic: 359.149263656
Chemical Formula C15H22FN3O6
InChI
InChI=1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1
IUPAC Name
pentyl N-{1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl}carbamate
Protein binding

< 60% (mainly albumin)

Toxicity Not Available
Half life

45-60 minutes for capecitabine and its metabolites.

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